Opportunity Information: Apply for RFA GH 16 007

The grant opportunity titled "Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1" (Funding Opportunity Number RFA GH 16 007) is a CDC-funded program designed to improve how countries prevent, detect, and respond to public health threats. Its central focus is on generating practical, decision-ready evidence through operations research and implementation science, so that Ministries of Health and other national stakeholders can make better-informed choices about building and improving public health protection systems. In plain terms, the CDC is looking to fund studies that help countries figure out what approaches work best in real-world settings, why they work, what barriers get in the way, and how to scale effective interventions in a sustainable way.

The overall purpose is global health security: strengthening national capacity to manage current and emerging threats, including outbreaks and the international spread of infectious diseases. Rather than emphasizing basic or laboratory discovery, this opportunity targets applied research that supports public health systems and programs, such as surveillance, outbreak investigation, emergency preparedness and response structures, workforce development, laboratory networks, and policy or operational improvements that make these systems function more reliably. The expectation is that funded projects will produce data and evidence that can directly shape strategies, interventions, and policies, especially those tied to strengthening public health protection infrastructure and performance.

A key eligibility constraint is geographic and operational. Projects are limited to countries where the CDC already has an established footprint, either through a CDC field office or a CDC presence created through deployment. This requirement signals that the work is intended to be closely connected to ongoing CDC partnerships and in-country implementation platforms, where findings can be used quickly and where collaboration with local health authorities is feasible.

The mechanism of support is a cooperative agreement, not a standard grant. That means the CDC anticipates substantial involvement in the project, typically including technical input, coordination, and collaboration during planning and execution, rather than simply providing funds and receiving periodic reports. This structure is commonly used when the agency expects to work closely with recipients to ensure alignment with program goals and to support translation of results into practice.

Administratively, the opportunity is categorized as discretionary funding and falls under the health activity category, with CFDA number 93.326. The eligible applicants are listed as "unrestricted," indicating that a broad range of organizations may apply, although in practice applicants still need to be able to carry out work in eligible countries and meet federal requirements. The opportunity was created on 2016-04-15, with an original closing date of 2016-06-28. The CDC anticipated making about 20 awards. The listed award ceiling is shown as 0, which typically indicates that a specific maximum per award was not stated in the summary field and would need to be confirmed in the full announcement text or budget guidance.

Overall, this funding opportunity is best understood as support for evidence-building projects that sit at the intersection of research and public health practice. The intended end product is not just a publication, but actionable findings that help national public health leadership strengthen systems and decision-making for outbreak prevention, early detection, and effective response, particularly in settings where CDC teams are already engaged alongside local partners.

  • The Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.326.
  • This funding opportunity was created on 2016-04-15.
  • Applicants must submit their applications by 2016-06-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 20 candidate(s).
  • Eligible applicants include: Unrestricted.
Apply for RFA GH 16 007

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Frequently Asked Questions (FAQs)

1) What is the title of this grant opportunity?

The opportunity is titled "Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1."

2) What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is RFA GH 16 007.

3) Which federal agency is funding this opportunity?

This is a CDC-funded program (Centers for Disease Control and Prevention).

4) What is the main goal of this funding opportunity?

The main goal is to improve how countries prevent, detect, and respond to public health threats by generating practical, decision-ready evidence that national stakeholders can use to strengthen public health protection systems.

5) What kinds of research does this opportunity prioritize?

It prioritizes operations research and implementation science that helps determine what approaches work best in real-world settings, why they work, what barriers affect implementation, and how effective interventions can be scaled sustainably.

6) Is this funding intended for basic or laboratory discovery research?

No. The emphasis is on applied research that supports public health systems and programs rather than basic or laboratory discovery.

7) What is meant by "global health protection" in this opportunity?

In this context, global health protection focuses on strengthening national capacity to manage current and emerging threats, including outbreaks and the international spread of infectious diseases.

8) What types of public health systems or program areas are specifically relevant?

Examples mentioned include surveillance, outbreak investigation, emergency preparedness and response structures, workforce development, laboratory networks, and policy or operational improvements that make these systems function more reliably.

9) What is the expected end product of funded projects?

Funded projects are expected to produce data and evidence that can directly shape strategies, interventions, and policies tied to strengthening public health protection infrastructure and performance. The intended end product is actionable findings, not just publications.

10) Are there geographic limitations on where projects can take place?

Yes. Projects are limited to countries where the CDC already has an established footprint, either through a CDC field office or a CDC presence created through deployment.

11) Why does the opportunity restrict projects to countries with an existing CDC footprint?

The requirement indicates the work is intended to connect closely to ongoing CDC partnerships and in-country implementation platforms, enabling quicker use of findings and feasible collaboration with local health authorities.

12) What type of funding mechanism is used (grant vs. cooperative agreement)?

The mechanism is a cooperative agreement, not a standard grant.

13) What does a cooperative agreement imply for the relationship with CDC?

A cooperative agreement means CDC anticipates substantial involvement in the project, such as technical input, coordination, and collaboration during planning and execution, rather than only providing funds and receiving periodic reports.

14) What is the funding category for this opportunity?

The opportunity is categorized as discretionary funding and falls under the health activity category.

15) What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.326.

16) Who is eligible to apply?

Eligible applicants are listed as "unrestricted," suggesting a broad range of organizations may apply, provided they can carry out work in eligible countries and meet federal requirements.

17) Does "unrestricted" eligibility mean any organization can apply regardless of capacity or location?

The listing indicates broad eligibility, but the opportunity still includes practical constraints, such as the need to implement work in CDC-presence countries and comply with federal requirements.

18) When was this funding opportunity created?

The opportunity was created on 2016-04-15.

19) What was the original closing date?

The original closing date was 2016-06-28.

20) How many awards did CDC anticipate making?

CDC anticipated making about 20 awards.

21) Is there a stated maximum award amount (award ceiling)?

The listed award ceiling is shown as 0, which typically indicates that a specific maximum per award was not stated in the summary field and would need to be confirmed in the full announcement text or budget guidance.

22) What is the practical focus of this opportunity in plain terms?

It funds studies that help countries figure out what works in real-world public health settings, what gets in the way, why certain approaches succeed, and how to expand successful interventions in a sustainable way.

23) What stakeholders are expected to use the evidence produced?

The evidence is intended to support Ministries of Health and other national stakeholders in making better-informed decisions about strengthening public health protection systems.

24) How should applicants think about the difference between research and public health practice for this opportunity?

This opportunity sits at the intersection of research and public health practice: it supports evidence-building activities designed to improve real program performance and decision-making for prevention, early detection, and response.

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