Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1 | RFA GH 16 007

Opportunity Information: Apply for RFA GH 16 007

The grant opportunity titled "Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1" (Funding Opportunity Number RFA GH 16 007) is a CDC-funded program designed to improve how countries prevent, detect, and respond to public health threats. Its central focus is on generating practical, decision-ready evidence through operations research and implementation science, so that Ministries of Health and other national stakeholders can make better-informed choices about building and improving public health protection systems. In plain terms, the CDC is looking to fund studies that help countries figure out what approaches work best in real-world settings, why they work, what barriers get in the way, and how to scale effective interventions in a sustainable way.

The overall purpose is global health security: strengthening national capacity to manage current and emerging threats, including outbreaks and the international spread of infectious diseases. Rather than emphasizing basic or laboratory discovery, this opportunity targets applied research that supports public health systems and programs, such as surveillance, outbreak investigation, emergency preparedness and response structures, workforce development, laboratory networks, and policy or operational improvements that make these systems function more reliably. The expectation is that funded projects will produce data and evidence that can directly shape strategies, interventions, and policies, especially those tied to strengthening public health protection infrastructure and performance.

A key eligibility constraint is geographic and operational. Projects are limited to countries where the CDC already has an established footprint, either through a CDC field office or a CDC presence created through deployment. This requirement signals that the work is intended to be closely connected to ongoing CDC partnerships and in-country implementation platforms, where findings can be used quickly and where collaboration with local health authorities is feasible.

The mechanism of support is a cooperative agreement, not a standard grant. That means the CDC anticipates substantial involvement in the project, typically including technical input, coordination, and collaboration during planning and execution, rather than simply providing funds and receiving periodic reports. This structure is commonly used when the agency expects to work closely with recipients to ensure alignment with program goals and to support translation of results into practice.

Administratively, the opportunity is categorized as discretionary funding and falls under the health activity category, with CFDA number 93.326. The eligible applicants are listed as "unrestricted," indicating that a broad range of organizations may apply, although in practice applicants still need to be able to carry out work in eligible countries and meet federal requirements. The opportunity was created on 2016-04-15, with an original closing date of 2016-06-28. The CDC anticipated making about 20 awards. The listed award ceiling is shown as 0, which typically indicates that a specific maximum per award was not stated in the summary field and would need to be confirmed in the full announcement text or budget guidance.

Overall, this funding opportunity is best understood as support for evidence-building projects that sit at the intersection of research and public health practice. The intended end product is not just a publication, but actionable findings that help national public health leadership strengthen systems and decision-making for outbreak prevention, early detection, and effective response, particularly in settings where CDC teams are already engaged alongside local partners.

• The Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Operations Research (Implementation Science) for Strengthening Global Health Protection Implementation: Amendment 1" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.326.
• This funding opportunity was created on 2016-04-15.
• Applicants must submit their applications by 2016-06-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 20 candidate(s).
• Eligible applicants include: Unrestricted.

Apply for RFA GH 16 007

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