Opportunity Information: Apply for PAR 17 329
The NIAID Physician-Scientist Pathway to Independence Award (K99/R00) is an NIH grant program from the National Institute of Allergy and Infectious Diseases designed to help clinically trained postdoctoral researchers move more quickly and successfully into independent academic research careers. Its central goal is to build and sustain a strong pipeline of physician-scientists by supporting the critical transition period between a mentored postdoctoral phase and the start of an independent, tenure-track (or equivalent) faculty position. By providing structured, phased support across that transition, NIAID aims to help early-career physician-scientists establish competitive, independent research programs in biomedical and health-related fields and to address the broader national shortage of physician-scientists.
The award uses the K99/R00 mechanism, which is specifically intended for a two-stage career progression. The first stage (K99) supports a mentored postdoctoral period where the candidate continues to build research expertise, publish, and develop a clear plan for independence with guidance from established investigators. The second stage (R00) provides support after the individual secures an independent faculty position, helping them launch their own lab or research program and compete effectively for longer-term research funding. In practice, this structure is meant to reduce the gap between training and independence by giving promising clinician-researchers both a defined runway and early independent funding once they are hired into an appropriate faculty role.
The opportunity is categorized as a discretionary grant in the health area, administered by NIH/NIAID, and is associated with CFDA numbers 93.855 and 93.856. The funding opportunity is identified as PAR-17-329, created on July 20, 2017, with an original closing date listed as May 7, 2020. The summary information provided does not specify an award ceiling or the expected number of awards, which typically means applicants would need to consult the full NIH announcement and budget guidelines for detailed financial limits, allowed costs, and project period rules.
Eligibility to apply is broad at the organizational level and includes many types of U.S.-based institutions and entities. Eligible applicants listed include public and private institutions of higher education, state and local governments (including counties, cities or townships, special districts, and independent school districts), federally recognized tribal governments, tribal organizations that are not federally recognized, public housing authorities/Indian housing authorities, nonprofits (both 501(c)(3) and non-501(c)(3) organizations), for-profit organizations other than small businesses, and small businesses. The announcement also explicitly calls out additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
At the same time, there are clear restrictions related to foreign participation. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) foreign institutions are not eligible to apply as applicant organizations. Non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined by the NIH Grants Policy Statement, are allowed, meaning a U.S. applicant organization may include certain well-justified foreign activities or collaborations within the project under NIH policy, even though a foreign institution cannot serve as the primary applicant.
Overall, this opportunity is best understood as a career-launch mechanism for outstanding postdoctoral physician-scientists: it is meant to support them first in a mentored environment and then, once they obtain a qualifying independent faculty position, to provide independent research support that helps them establish a durable, competitive research trajectory in areas aligned with NIAID’s biomedical mission.Apply for PAR 17 329
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIAID Physician-Scientist Pathway to Independence Award (K99/R00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855, 93.856.
- This funding opportunity was created on 2017-07-20.
- Applicants must submit their applications by 2020-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): NIAID Physician-Scientist Pathway to Independence Award (K99/R00)
What is the NIAID Physician-Scientist Pathway to Independence Award (K99/R00)?
It is an NIH grant program administered by the National Institute of Allergy and Infectious Diseases (NIAID) designed to help clinically trained postdoctoral researchers transition more quickly and successfully into independent academic research careers. It supports the key career step from mentored postdoctoral research to an independent faculty position.
What is the main purpose of this award?
The central goal is to build and sustain a strong pipeline of physician-scientists by supporting the critical transition period between a mentored postdoctoral phase and the start of an independent, tenure-track (or equivalent) faculty position. The program also aims to help address the broader national shortage of physician-scientists.
Who is this award intended to help?
This opportunity is intended for clinically trained postdoctoral researchers (physician-scientists) who are working toward independence and want structured support as they move from mentored training to launching an independent academic research program.
What does "K99/R00" mean in this program?
K99/R00 refers to a two-stage NIH career development and research support mechanism. The first phase (K99) supports a mentored postdoctoral period, and the second phase (R00) supports the individual after they secure an independent faculty position.
How does the two-stage structure work?
The award is designed as a defined progression across two phases. In the K99 mentored phase, the candidate continues postdoctoral training with guidance from established investigators. In the R00 phase, support continues after the awardee obtains an independent, tenure-track (or equivalent) faculty position, helping them launch their own research program and compete for longer-term funding.
What is the goal of the K99 (mentored) phase?
The K99 phase supports a mentored postdoctoral period where the candidate builds research expertise, publishes, and develops a clear plan for independence with guidance from established investigators.
What is the goal of the R00 (independent) phase?
The R00 phase provides support after the individual secures an independent faculty position, helping them launch an independent lab or research program and compete effectively for longer-term research funding.
Why does NIAID use a phased approach for this award?
The phased structure is intended to reduce the gap between training and independence by providing a mentored runway during the postdoctoral period and then early independent funding once the individual is hired into an appropriate faculty role.
What kinds of research areas does this award support?
The opportunity supports independent research programs in biomedical and health-related fields aligned with NIAID's mission. The summary describes it broadly as supporting biomedical and health-related research careers.
What type of grant is this categorized as?
It is categorized as a discretionary grant in the health area and is administered by NIH/NIAID.
What are the CFDA numbers associated with this funding opportunity?
The opportunity is associated with CFDA numbers 93.855 and 93.856.
What is the funding opportunity ID?
The funding opportunity is identified as PAR-17-329.
When was this opportunity created and what closing date is listed in the summary?
The summary states it was created on July 20, 2017, and lists an original closing date of May 7, 2020.
Does the summary specify an award ceiling or number of awards?
No. The summary information provided does not specify an award ceiling or the expected number of awards.
Where would applicants typically find financial limits and budget rules?
Because the summary does not list an award ceiling or number of awards, applicants would typically need to consult the full NIH announcement and applicable NIH budget guidelines for financial limits, allowed costs, and project period rules.
What organizations are eligible to apply?
Eligibility is broad at the organizational level and includes many types of U.S.-based institutions and entities, including public and private institutions of higher education; state and local governments; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits (501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; and small businesses.
Are specific institution types explicitly called out as eligible?
Yes. The announcement explicitly calls out Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; and U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply as the primary applicant?
No. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) foreign institutions are not eligible to apply as applicant organizations.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are also not eligible to apply as applicant organizations.
Are foreign components allowed at all under this opportunity?
Yes. Foreign components, as defined by the NIH Grants Policy Statement, are allowed. This means a U.S. applicant organization may include certain well-justified foreign activities or collaborations within the project under NIH policy, even though a foreign institution cannot serve as the primary applicant.
What is the overall career impact this award is designed to have?
It is designed as a career-launch mechanism for outstanding postdoctoral physician-scientists by supporting them first in a mentored environment and then providing independent research support once they obtain a qualifying faculty position, helping them establish a durable, competitive independent research trajectory.
What kind of faculty position is expected for the transition to the R00 phase?
The summary describes the transition as occurring when the individual secures an independent, tenure-track (or equivalent) faculty position.
What problem does this program aim to address at a national level?
The program is described as helping address the broader national shortage of physician-scientists by strengthening the pipeline into independent research careers.
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